Issue 8, 2004

Symmetrical dinuclear complexes with high DNA affinity based on [Ru(dpq)2(phen)]2+

Abstract

Symmetrical homometallic dinuclear complexes of the type [{Ru(dpq)2}2(phen–SOS–phen)]4+, with a flexible 2-mercaptoethyl ether linker joining the two [Ru(dpq)2(phen)]2+-based sub-units, have DNA dissociation constants (Kd) in the nM range.

Graphical abstract: Symmetrical dinuclear complexes with high DNA affinity based on [Ru(dpq)2(phen)]2+

Supplementary files

Article information

Article type
Communication
Submitted
05 Jan 2003
Accepted
11 Mar 2004
First published
23 Mar 2004

Chem. Commun., 2004, 1018-1019

Symmetrical dinuclear complexes with high DNA affinity based on [Ru(dpq)2(phen)]2+

J. Aldrich-Wright, C. Brodie, E. C. Glazer, N. W. Luedtke, L. Elson-Schwab and Y. Tor, Chem. Commun., 2004, 1018 DOI: 10.1039/B316917K

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