Issue 14, 2003

Tandem olefin metathesis/hydrogenation at ambient temperature: activation of ruthenium carbene complexes by addition of hydrides

Abstract

Sodium hydride activates ruthenium carbene complexes to catalyze hydrogenation reactions subsequent to ring closing olefin metathesis. Under these conditions, hydrogenation of cyclopentenols proceeds smoothly at ambient temperature and under 1 atm of hydrogen in toluene. An alternative protocol was developed that involves the formation of hydrogen in situ by reaction of excess sodium hydride with protic functional groups and water.

Graphical abstract: Tandem olefin metathesis/hydrogenation at ambient temperature: activation of ruthenium carbene complexes by addition of hydrides

Article information

Article type
Paper
Submitted
28 Mar 2003
Accepted
02 Jun 2003
First published
16 Jun 2003

Org. Biomol. Chem., 2003,1, 2512-2517

Tandem olefin metathesis/hydrogenation at ambient temperature: activation of ruthenium carbene complexes by addition of hydrides

B. Schmidt and M. Pohler, Org. Biomol. Chem., 2003, 1, 2512 DOI: 10.1039/B303441K

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