Issue 6, 2003
From the journal:

Organic & Biomolecular Chemistry

Luminescent nonacoordinate cationic lanthanide complexes as potential cellular imaging and reactive probes

Juan C. Frias,a   Gabriella Bobba,a   Martin J. Cann,b   Chris J. Hutchisonb  and  David Parker*a  

* Corresponding authors

a Department of Chemistry, University of Durham, South Road, Durham, UK
E-mail: David.Parker@durham.ac.uk

b School of Biological Sciences, University of Durham, Science Laboratories, Durham, UK

Abstract

Nonacoordinate Δ- and Λ-Eu and Tb complexes have been tested as imaging and reactive probes in mouse fibroblast (NIH 3T3) cells. The uptake of these complexes by the cells was assessed by fluorescence microscopy. Complex-induced DNA damage was studied by gel electrophoresis and shown to be a function of complex chirality.

Graphical abstract: Luminescent nonacoordinate cationic lanthanide complexes as potential cellular imaging and reactive probes

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Article information

DOI
https://doi.org/10.1039/B301385P
Article type
Communication
Submitted
04 Feb 2003
Accepted
12 Feb 2003
First published
21 Feb 2003

Org. Biomol. Chem., 2003,1, 905-907

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Luminescent nonacoordinate cationic lanthanide complexes as potential cellular imaging and reactive probes

J. C. Frias, G. Bobba, M. J. Cann, C. J. Hutchison and D. Parker, Org. Biomol. Chem., 2003, 1, 905 DOI: 10.1039/B301385P

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