Direct formation of 2,4-disubstituted tetrahydropyranols in water mediated by an acidic solid resin
Abstract
Amberlite® IR-120 Plus resin, a readily regenerated acidic solid resin, mediates the formation of tetrahydropyranol derivatives in water. Various aldehydes were reacted with homoallyl alcohol under the reaction conditions to yield the desired tetrahydropyranol derivatives in moderate to good yields.