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Issue 3, 2003
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A reagentless electrochemical biosensor based on a protein scaffold

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Abstract

Apo-myoglobin, labeled with the environmentally sensitive redox probe RuII(NH3)4(1,10-phenanthroline-5-maleimide)2+, was immobilized onto gold electrodes modified with 11-mercaptoundecanoic acid and subsequently labeled with biotin; avidin binding to the immobilized biotin was specifically and quantitatively detected by a change in cyclic voltammetry of the co-immobilized probe.

Graphical abstract: A reagentless electrochemical biosensor based on a protein scaffold

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Publication details

The article was received on 26 Sep 2002, accepted on 04 Dec 2002 and first published on 02 Jan 2003


Article type: Communication
DOI: 10.1039/B209452E
Citation: Chem. Commun., 2003,0, 338-339
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    A reagentless electrochemical biosensor based on a protein scaffold

    S. D. Jhaveri, J. M. Mauro, H. M. Goldston, C. L. Schauer, L. M. Tender and S. A. Trammell, Chem. Commun., 2003, 0, 338
    DOI: 10.1039/B209452E

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