Partial reduction of 3-heteroatom substituted 2-furoic acids: the role of an ortho group in viability and stereoselectivity
Abstract
The synthesis of 2-furoic acid derivatives containing both 3-methoxy and 3-TMS groups is described. Reductive
* Corresponding authors
a
Dyson Perrins Laboratory, South Parks Road, Oxford, UK
E-mail:
timothy.donohoe@chem.ox.ac.uk
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b Department of Chemistry, University of Manchester, Oxford Road, Manchester, UK
c Department of Chemistry, Roche Discovery Welwyn, Broadwater Road, Welwyn Garden City, Herts, UK
The synthesis of 2-furoic acid derivatives containing both 3-methoxy and 3-TMS groups is described. Reductive
T. J. Donohoe, A. A. Calabrese, J. Guillermin, Christopher. S. Frampton and D. Walter, J. Chem. Soc., Perkin Trans. 1, 2002, 1748 DOI: 10.1039/B203437A
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