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Issue 23, 2002
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Asymmetric synthesis of (1R,2S,3R)-γ-methyl-cis-pentacin by a kinetic resolution protocol

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Abstract

The asymmetric synthesis of (1R,2S,3R)-3-methyl-2-aminocyclopentane carboxylic acid has been achieved via kinetic resolution of racemic tert-butyl 3-methyl-cyclopentene-1-carboxylate with homochiral lithium (S)-N-benzyl-N-α-methylbenzylamide.

Graphical abstract: Asymmetric synthesis of (1R,2S,3R)-γ-methyl-cis-pentacin by a kinetic resolution protocol

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Publication details

The article was received on 03 Oct 2002, accepted on 22 Oct 2002 and first published on 05 Nov 2002


Article type: Communication
DOI: 10.1039/B209728C
Citation: Chem. Commun., 2002,0, 2910-2911
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    Asymmetric synthesis of (1R,2S,3R)-γ-methyl-cis-pentacin by a kinetic resolution protocol

    S. Bailey, S. G. Davies, A. D. Smith and J. M. Withey, Chem. Commun., 2002, 0, 2910
    DOI: 10.1039/B209728C

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