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Issue 18, 2001
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Identification of Tyr58 as the proton donor in the aspartate-α-decarboxylase reaction

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Abstract

The decarboxylation of L-aspartate by E. coliL-aspartate-α-decarboxylase (ADC) is shown to occur with retention of configuration; analysis of the protein structure identifies Tyr58 as the proton donor in the decarboxylation mechanism.

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Publication details

The article was received on 10 Jul 2001, accepted on 30 Jul 2001 and first published on 29 Aug 2001


Article type: Communication
DOI: 10.1039/B106090M
Citation: Chem. Commun., 2001, 1760-1761
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    Identification of Tyr58 as the proton donor in the aspartate-α-decarboxylase reaction

    S. A. Saldanha, L. M. Birch, M. E. Webb, B. K. Nabbs, F. von Delft, A. G. Smith and C. Abell, Chem. Commun., 2001, 1760
    DOI: 10.1039/B106090M

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