Issue 17, 2000

C-18 Hydroxylation of gibberellins

Abstract

A protocol for the hydroxylation of the 18-methyl group in gibberellins has been developed, as demonstrated by the successful synthesis of 18-hydroxy GA4 methyl ester by means of a tandem process involving the conjugate addition of alkoxide to the α-methylene lactone moiety of a ring A-seco-gibberellin followed by an intramolecular aldol reaction.

Article information

Article type
Communication
Submitted
26 Jul 2000
Accepted
02 Aug 2000
First published
14 Aug 2000

J. Chem. Soc., Perkin Trans. 1, 2000, 2893-2894

C-18 Hydroxylation of gibberellins

L. N. Mander and R. J. Thomson, J. Chem. Soc., Perkin Trans. 1, 2000, 2893 DOI: 10.1039/B006044P

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