Issue 17, 2000
From the journal:

Chemical Communications

The use of hydrazones for efficient mannich type coupling with aldehydes and secondary amines

Valérie Atlan,a   Hugues Bienaymé,a   Laurent El Kaim*a  and  Adinath Majeea  

* Corresponding authors

a Laboratoire Chimie et Procédés, Ecole Nationale Supérieure de Techniques Avancées, 32 Bd Victor, Paris, France.
E-mail: elkaim@ensta.fr

Abstract

The Mannich reaction of hydrazones originally limited to the coupling of hydrazones with formaldehyde has been extended to a large variety of aldehydes through appropriate selection of experimental conditions; in conjunction with the Japp–Klingmann reaction, this process provides an efficient synthetic tool for the formation of carbon–carbon bonds.

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Article information

DOI
https://doi.org/10.1039/B002750M
Article type
Communication
Submitted
06 Apr 2000
Accepted
04 Jul 2000
First published
03 Aug 2000

Chem. Commun., 2000, 1585-1586

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The use of hydrazones for efficient mannich type coupling with aldehydes and secondary amines

V. Atlan, H. Bienaymé, L. El Kaim and A. Majee, Chem. Commun., 2000, 1585 DOI: 10.1039/B002750M

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