Acidic clay catalyzed reaction of malononitrile derivatives with an excess of 1,2-aminoalcohol furnishes mono-oxazolines selectively; a simple strategy to prepare 2,2-dialkyl-3-aminopropionic acid derivatives is presented.
G. K. Jnaneshwara, V. H. Deshpande and A. V. Bedekar, J. Chem. Res. (S), 1999, 252 DOI: 10.1039/A807016D
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