Efficient RhII binaphthol phosphate catalysts for enantioselective intramolecular tandem carbonyl ylide formation–cycloaddition of α-diazo-β-keto esters

Abstract

Catalytic enantioselective tandem carbonyl ylide formation–cycloadditions of α-diazo-β-keto ester 1 using 0.5 mol% dirhodium tetrakis(1,1′-binaphthyl-2,2′-diyl phosphate) catalysts 7–9 and 14 to give the cycloadduct 3 in good yields and up to 90% ee are described.