Synthesis of a novel tetracyclic acridine. A sulphoxide-based route to the 1,2,3,4-tetrahydrobenzo[b][1,8]phenanthroline ring system
Abstract
The ambit of the classical acridine synthesis, via acid-mediated cyclisation of 2-oxodiphenylamines, has been extended to include a sulphoxide-containing precursor. This adaption produced the tetracyclic system of 1 in a single step from 25.