Issue 0, 1986

Synthesis of the taxane ring system using an intramolecular Diels–Alder reaction of a 2-substituted diene

Abstract

A synthesis of (1R/S,3R/S,8S/R)-8-methyltricyclo[9.3.1.03,8]pentadec-11-en-2-one, which is the ring system of the taxane natural products and contains 3 chiral centres having the required relative configuration, is described.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1986, 1303-1309

Synthesis of the taxane ring system using an intramolecular Diels–Alder reaction of a 2-substituted diene

P. A. Brown and P. R. Jenkins, J. Chem. Soc., Perkin Trans. 1, 1986, 1303 DOI: 10.1039/P19860001303

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