Masking the carboxy group as a 2,6,7-trioxabicyclo[2.2.2]octane: application to the synthesis of alkylcobaloximes containing ester and carboxy groups
Abstract
The hydrolytic stability of 2,6,7-trioxabicyclo-[2.2.2]octanes towards aqueous acid is intermediate between that of 1,1,1-triethoxyethane and 1-methyl-2,8,9-trioxa-adamantane; a synthetic application of this trioxabicyclo-octane group as a masked carboxy function is described.