Issue 13, 1970

Hypotensive amines: unbridged cyclohexane analogues of mecamylamine

Abstract

Some polyalkylcyclohexylamines related to pempidine have been prepared as potential ganglion-blocking agents, and their methylation has been examined. An N-formyl derivative, prepared via the Ritter reaction, showed anomalous behaviour on hydrolysis. No useful pharmacological activity was found.

Article information

Article type
Paper

J. Chem. Soc. C, 1970, 1845-1847

Hypotensive amines: unbridged cyclohexane analogues of mecamylamine

E. Lunt and W. R. Wragg, J. Chem. Soc. C, 1970, 1845 DOI: 10.1039/J39700001845

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