A series of effective tumour-inhibitory polymeric compounds has been prepared by allowing melphalan [p-di-(2-chloroethyl)aminophenyl-L-alanine] ethyl or benzyl ester to initiate the polymerisation and copolymerisation of N-carboxy-amino-acid anhydrides in anhydrous solution. The results of anti-tumour tests are presented.
M. Szekerke, R. Wade and F. Bergel, J. Chem. Soc. C, 1968, 1792 DOI: 10.1039/J39680001792
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