Issue 23, 2018

FeCl3 or MeSO3H-promoted multicomponent reactions for facile synthesis of structurally diverse furan analogues

Abstract

An intriguing conversion of arylglyoxal, cyclic dicarbonyl compounds and phenols to diverse furan analogues under FeCl3 or MeSO3H catalysis is reported. Utilizing this synthetic protocol, a variety of furan analogues could be easily obtained in moderate to good yields with different substituted patterns by varying the reaction medium. Atom-economical characteristics and mild conditions of this method are in accord with the concept of modern green chemistry.

Graphical abstract: FeCl3 or MeSO3H-promoted multicomponent reactions for facile synthesis of structurally diverse furan analogues

Supplementary files

Article information

Article type
Paper
Submitted
21 Apr 2018
Accepted
16 May 2018
First published
18 May 2018

Org. Biomol. Chem., 2018,16, 4279-4287

FeCl3 or MeSO3H-promoted multicomponent reactions for facile synthesis of structurally diverse furan analogues

X. Chang, X. Zhang and Z. Chen, Org. Biomol. Chem., 2018, 16, 4279 DOI: 10.1039/C8OB00942B

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