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Correction: Conformationally restricted benzothienoazepine respiratory syncytial virus inhibitors: their synthesis, structural analysis and biological activities

Euan A. F. Fordyce *a, S. Fraser Hunt a, Damien Crepin a, Stuart T. Onions a, Guillaume F. Parra a, Chris J. Sleigh a, John King-Underwood b, Harry Finch c and John Murray *c
aSygnature Discovery Ltd., BioCity, Nottingham, NG1 1GF, UK. E-mail: e.fordyce@sygnaturediscovery.com; Tel: +44 (0)1159415401
bCompChem Resource, Old Cottage Hospital, Homend, Ledbury, Herefordshire, HR8 1ED, UK
cPulmocide Ltd., 52 Princes Gate, Exhibition Road, South Kensington, London, SW7 2PG, UK. E-mail: john@pulmocide.com; Tel: +44 (0)2037639484

Received 19th March 2018 , Accepted 19th March 2018

First published on 26th March 2018


Correction for ‘Conformationally restricted benzothienoazepine respiratory syncytial virus inhibitors: their synthesis, structural analysis and biological activities’ by Euan A. F. Fordyce et al., Med. Chem. Commun., 2018, DOI: 10.1039/c8md00033f.


The authors regret that the information in note 17 in the References section of the manuscript gives an incorrect ratio of the isomers. The correct information is as follows:

17. The major impurity present in the mixture (29% isolated yield) was the corresponding propenyl thiophene 24, present as a 4[thin space (1/6-em)]:[thin space (1/6-em)]1 mixture of trans[thin space (1/6-em)]:[thin space (1/6-em)]cis isomers, which presumably form via elimination of triphenylphosphine oxide from the intermediate alkyloxytriphenylphosphonium species.

In addition, the wording in the Acknowledgements should be amended as follows:

The authors would like to thank Dr Kaz Ito (Pulmocide Ltd.) and Heather Allen (Pulmocide Ltd.) for the provision of the biological screening data for compounds 8a, 14 and 20.

The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.


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