Stefan
Schünemann
,
Ferdi
Schüth
and
Harun
Tüysüz
*
Max-Planck-Institut für Kohlenforschung, Kaiser-Wilhelm-Platz 1, 45470 Mülheim an der Ruhr, Germany. E-mail: tueysuez@kofo.mpg.de
First published on 5th October 2017
Glycerol is a major by-product of the biodiesel production and is therefore produced in high quantities. While currently there are limited possible applications for this highly functionalized molecule, glycerol can be a cheap and abundant feedstock for value-added products that are accessible by selective oxidation. Usually, the selective oxidation of glycerol utilizes expensive noble metal catalysts, such as Au, Pt, and Pd. Here we report the selective oxidation of glycerol in basic media, using ordered mesoporous Cu–Al2O3 catalysts with various Cu loadings prepared by a facile soft-templating method. The materials were characterized in detail by nitrogen physisorption, vis-NIR spectroscopy, EDX, low- and wide-angle XRD, XPS, and TEM. Subsequently the reaction conditions for glycerol oxidation were optimized. The catalytic oxidation of glycerol yields C3 products, such as glyceric acid and tartronic acid, and also C2 and C1 products, such as glycolic acid, oxalic acid, and formic acid. Moreover, the role of the solvent on the catalytic reaction was investigated, and the addition of various co-solvents to the aqueous reaction mixture was found to increase the initial reaction rate up to a factor of three. The trends of the initial reaction rates correlate well with the polarity of the water/co-solvent mixtures. The prepared Cu–Al2O3 catalysts are a more cost-efficient and environmentally viable alternative to the reported noble metal catalysts.
The large supply of glycerol from biodiesel production and the lack of utilization of this molecule, together with its high functionalization, offer profitable possibilities for upgrading reactions. In this context, selective oxidation reactions are of particular interest as this reaction opens pathways to produce a variety of value-added products.11 Such products include glyceric, glycolic, tartronic, oxalic, and formic acids, which are used, for example, as pharmaceuticals, cosmetics, and intermediates in the chemical industry.11 Also, the catalytic formation of formic acid from biomass recently has attracted attention for energy conversion related applications.12–14 Active catalysts for this reaction most often are composed of supported noble metal nanoparticles, such as Au,15–21 Pd,15–17,22,23 Pt,15–17,24–29 Ag,30 and alloys17,31–33 thereof, which were frequently demonstrated to catalyze selective glycerol oxidation in neutral and basic media. Furthermore, noble metal/Cu alloys are also reported as active catalysts for the selective oxidation of glycerol.34–36 Despite the variety of possible noble metal catalysts, more abundant and cost-efficient catalysts are highly desirable. An attractive alternative to noble metals in selective oxidation reactions is copper, which was demonstrated to be active for the selective oxidation of various alcohols and polyols.37–41 However, there are only few reports on selective oxidation of glycerol in basic media with non-noble metal catalysts, such as with the toxic and carcinogenic cobalt,42–44 layered double hydroxide supported transition metals,45–47 or using hydrogen peroxide instead of molecular oxygen as an oxidizing agent.48,49
Key factors for the fabrication of efficient supported catalysts are firstly a high dispersion of the active component on the support material; secondly, high surface areas of the support; and thirdly, large porosity to allow efficient diffusion of reactants to the active centers. A particularly intriguing support for Cu based catalysts is γ-Al2O3, in which Cu cations are atomically dispersed by occupying the tetrahedral and octahedral sites of Al2O3.50 In this context, ordered mesoporous Cu–γ-Al2O3 is of special interest for catalytic applications due to the fine dispersion of copper in the γ-Al2O3 matrix and its high surface area.51
High concentrations of glycerol typically lead to highly viscous liquids, and therefore liquid phase catalytic reactions involving glycerol are usually carried out with relatively low concentrations between 0.05 M and 0.3 M in order to avoid mass transport limitations in the solvent. The solvent of choice is typically water. However, various studies indicate that the solvent has a strong influence on the catalytic activity in various heterogeneously catalyzed alcohol oxidations39,52,53 and other reactions54–58 with vastly altered activities and selectivities. Solvents can influence the activity and selectivity of a reaction, for example, by changing the solvent shell around the reactants to allow facilitated catalyst/solvent interactions,58 by varying the diffusion and adsorption properties of reactants within the catalyst pores39,52,53,59 by facilitating cation solvation, resulting in less competition between the solvent and reactant for the base,60 and solvent induced changes of the pKa.61,62
We synthesized ordered mesoporous Cu–Al2O3 catalysts for the selective oxidation of glycerol with Cu loadings between 0 and 20 wt% using a facile soft-templating approach. After detailed characterization comprising N2 physisorption, small-angle X-ray diffraction (XRD), wide-angle XRD, energy dispersive X-ray (EDX) spectroscopy, transmission electron microscopy (TEM), and vis-NIR spectroscopy, the catalysts were used for the selective oxidation of glycerol in the aqueous phase. The reaction conditions were optimized and various co-solvents (methanol, ethanol, 1-propanol, and tert-butanol) were added to the aqueous reaction medium with volumetric concentrations of 5, 20, 35, and 50%. The catalytic performance of the material was significantly enhanced by the addition of a co-solvent due to the reduced polarity which facilitates the interaction between the polar glycerol molecule and the catalyst's surface, with the exception of methanol.
The Brunauer–Emmett–Teller (BET) surface areas of the catalysts prepared with P123 are between 195 m2 g−1 and 45 m2 g−1 and steadily decrease as the copper content increases from 0% to 20% (Table S1†). The decreasing surface area indicates that the incorporation of copper hinders the formation of well-ordered mesoporous Al2O3 around the tubular P123 micelles. This is also evident from the Barrett–Joyner–Halenda (BJH) pore size distribution derived from the desorption branch of the isotherms (Fig. S2b†). The samples 0-Cu, 1-Cu, and 5-Cu possess very narrow pore size distributions with a maximum at approximately 4 nm, which is a typical pore diameter observed for materials synthesized with P123 as the structure directing agent.51 However, as the Cu loading increases to 10%, the pore size distribution becomes broader, and no distinct peak at 4 nm can be observed as a result of the hindered ordering around the P123 micelles. This effect becomes more pronounced at a Cu loading of 20% for which a very broad pore size distribution is observed. Even broader pore size distributions are observed for 5-Cu-sf and 5-Cu-Comm. The large mesopores observed in these samples are likely to originate from voids between individual particles, rather than from pores inside the particles.
Small angle XRD further confirms a loss of ordering in the pore structure when the Cu content is increased above 10 wt% (Fig. 1a). The incorporation of Cu into the Al2O3 matrix also influences the crystallinity of the catalysts.51 The wide angle XRD pattern of the copper free 0-Cu shows very broad reflections at positions that can be assigned to the γ-phase of Al2O3 (Fig. 1b). As the Cu content increases, the reflections become narrower, which indicates larger primary crystallites. Also, at a Cu content of 20 wt%, the positions of the reflections shift to lower angles and thus become more related to the CuAl2O4 spinel structure (Fig. 1b). As a result of the absence of a structure directing agent during the synthesis, 5-Cu-sf consists of much larger primary crystallites compared to 5-Cu, indicated by sharper reflections in the XRD patterns (Fig. 1b). Furthermore, the XRD patterns do not show additional reflections from Cu species like CuO, even for very high Cu loadings of 20 wt%.
Fig. 1 Small angle (a) and wide angle (b) XRD patterns of copper aluminum oxide with various copper amounts – 0-Cu, 1-Cu, 5-Cu, 5-Cu-sf, 10-Cu, and 20-Cu. |
The ordered pore structure and fine Cu dispersion through the structure were further studied by transmission electron microscopy (Fig. 2a) and EDX maps of 5-Cu (Fig. 2b–e). The micrograph in Fig. 2a shows a well-ordered and parallel aligned tubular mesopore structure, which is typical for the hexagonally ordered mesoporous materials like SBA-15. The EDX maps of oxygen (Fig. 2c), aluminum (Fig. 2d), and copper (Fig. 2e) of the particle shown in Fig. 2b show that copper is uniformly dispersed throughout the particle. Conclusively, the varied lattice parameters upon Cu incorporation (as depicted by the shifted XRD reflection peaks), the absence of XRD signals from other Cu species, the electron microscopy images, and the EDX maps strongly suggest that Cu is fully incorporated into the structure of Al2O3.
Fig. 2 Transmission electron micrograph of 5-Cu (a). Scanning electron microscopy image (b) and element mapping of oxygen (c), aluminum (d), and copper (e) of 5-Cu. |
The structure of γ-Al2O3 is under debate in the literature; however, most studies suggest a cubic defect spinel structure comprising a densely packed array of O2− anions in which Al3+ randomly occupies some of the octahedral (Oh) and tetrahedral (Td) sites.66–68 Cu2+ cations can occupy the remaining voids in the Oh and Td sites of the closely packed O2− array.
The possibility for Cu2+ to occupy the void sites in the O2− lattice results in the high dispersion of Cu2+ within γ-Al2O3. The d–d transition energies of Cu2+ with a d9 electron configuration are different for octahedrally and tetrahedrally coordinated Cu2+ cations and can be qualitatively probed by vis-NIR spectroscopy.66 Octahedrally coordinated Cu2+ absorbs at approximately 720 nm, whereas tetrahedrally coordinated Cu2+ absorbs photons with wavelengths of approximately 1500 nm.66 The Kubelka–Munk transformation of the diffuse reflectance vis-NIR spectrum for 0-Cu does not show any peaks (Fig. 3). At a very low Cu content of 1 wt%, only the minor peak at the wavelength of 720 nm is observed. The samples 5-Cu, 5-Cu-sf, 10-Cu, and 20-Cu show pronounced absorption bands at approximately 720 nm, which can be assigned to d–d transitions of octahedrally coordinated Cu2+ cations. In addition to that, 20-Cu and, to a lesser extent, 10-Cu also show pronounced absorption bands at approximately 1500 nm, which belong to d–d transitions of tetrahedrally coordinated Cu2+ cations. Thus, the vis-NIR spectra suggest that at Cu contents exceeding 10 wt%, Cu2+ begins to occupy tetrahedral sites, which are commonly considered to be less active for many redox reactions.50,66,69
Fig. 3 Kubelka–Munk transformation of the diffuse reflectance vis-NIR spectra of 0-Cu, 1-Cu, 5-Cu, 5-Cu-sf, 10-Cu, and 20-Cu. |
Additionally, XPS measurements of 5-Cu show pronounced satellite peaks of the Cu 2p3/2 and 2p1/2 signals at binding energies of 943 eV and 963 eV, respectively, which indicate the presence of Cu2+ in the sample (Fig. S3†). Since all catalysts were prepared without a reduction step, no metallic Cu was observed from XPS measurements in the samples. Conclusively, the physical characterization of the prepared catalysts reveals that the incorporation of Cu into the Al2O3 matrix has a detrimental effect on important physical properties of a solid catalyst, such as the surface area and pore size distribution. Additionally, the vis-NIR spectra show that at Cu contents exceeding 10 wt%, Cu begins to occupy the tetrahedral voids, which are considered to be less catalytically active sites for redox reactions. The results therefore suggest the existence of an optimal Cu content between 5 and 10 wt%.
The glycerol conversion of 5-Cu-sf, which was synthesized without P123 as a structure directing agent, and that of 5-Cu-Comm, which was synthesized from a commercial Al2O3 source, are two times lower than that of 5-Cu, which demonstrates the superior catalytic properties of the ordered mesoporous structure. The lower activities of these non-ordered samples may result from the lower BET surface areas of 5-Cu-sf (30 m2 g−1) and 5-Cu-Comm (80 m2 g−1) compared to 5-Cu (145 m2 g−1) and the absence of mesoporosity that may cause diffusion and mass transportation limitations in these materials. In summary, the observed trends of the catalytic activity seem to be affected by mainly three factors which are the surface area, the total Cu2+ concentration and the ratio between tetrahedrally and octahedrally coordinated Cu2+. These initial catalytic experiments confirm the superior catalytic activity of 5-Cu as a result of the beneficial coordination of Cu2+ into the octahedrally coordinated sites and its superior textural properties indicated by the high surface area. Therefore, all further experiments were performed with the 5-Cu catalyst.
As a next step, different reaction conditions were screened to optimize the reaction conditions. Fig. S4a† shows the glycerol conversion after 3 h at different temperatures. As expected, higher temperatures lead to increased reaction rates, which caused a steady increase in the glycerol conversion from 10 to 44% as the reaction temperature is increased from 60 to 90 °C (Fig. S4a†). The influence of oxygen pressure on the glycerol conversion was examined to exclude operation conditions in which the oxygen concentration in the liquid phase, or oxygen mass transfer, could limit the glycerol conversion. Glycerol oxidation experiments with 5-Cu were performed at different oxygen pressures up to 15 bar and no change in conversion above 10 bar was observed (Fig. S4b†), which shows that, at oxygen pressures above 10 bar, the reaction order approaches pseudo zero order towards oxygen. It should be noted that under these operating conditions, the oxygen concentration in the liquid phase is approximately proportional to the oxygen pressure in the gas phase.71 It is well known that the pH-value of the reaction medium has a strong impact on the catalytic activity of noble metal catalysts in glycerol oxidation. For example, Pt- and Pd-based catalysts are active in both acidic and basic media, whereas Au-based catalysts are almost exclusively active in basic media.1,15,21 However, less is known about the effect of the pH on the catalytic activity of Cu-based catalysts in glycerol oxidation reactions. Thus, the influence of the pH on the glycerol conversion was studied at various molar NaOH to glycerol ratios (4:1, 2:1, 1:1, 0:1), which gave pH values of 13.1, 12.8, 12.6, and 7.0, respectively. As shown in Fig. S4c,† in neutral media without the addition of NaOH, no conversion of glycerol can be observed. As the NaOH concentration and pH increase, the glycerol conversion increases proportionally to the NaOH concentration. It has been shown for Au catalysts, that the first step of the catalytic cycle is the adsorption of glycerolate, rather than of glycerol, on the catalyst's surface.72 Since the conversion of glycerol is approximately proportional to the NaOH concentration and therefore also to the glycerolate concentration, it is reasonable to assume that glycerol needs to be deprotonated in the first step of the Cu catalyzed reaction, either in the solvent, or at the catalyst surface, as it is also the case for Au-based catalysts.72 To exclude operation under mass transfer limited conditions, the conversion at different stirring speeds was evaluated. As depicted in Fig. S4d,† no change in conversion is observable between the reactions with stirring speeds of 250 rpm and 750 rpm, which excludes operation under mass transfer limitations under standard reaction conditions of 750 rpm. The product selectivity is a key parameter in catalytic reactions. The plot of the selectivity over the reaction time (Fig. 5) shows that the selectivity towards the C3 products glyceric acid and tartronic acid increases within the first 1 to 1.5 h. At longer reaction times, increasing C–C cleavage into the C2 and C1 products oxalic acid, glycolic acid, and formic acid sets in, as it is also observed in the use of other non-noble42,49 and noble73 metal catalysts.
In the selectivity–time profiles, it is remarkable to see that the selectivity towards glycolic and glyceric acid follows the same time profile with steeply increasing selectivity in the first reaction hour. The formation of the primary reaction product glyceric acid proceeds via the intermediates glyceraldehyde and dihydroxyacetone, respectively, which are unstable under the basic reaction conditions. In the literature, the formation of glycolic acid is suggested to proceed via decarboxylation of tartronic acid to yield CO2 as a side product.74,75 However, since large amounts of glycolic acid are being formed within the first reaction hour, where the carbon mass balance is practically closed, glycolic acid is likely to be formed as a primary reaction product from glycerol via glyceraldehyde or dihydroxyacetone as intermediates, as it was also reported previously.30,44,76,77 The direct generation of glycolic acid from glycerol as a primary reaction product is also supported by the formation of large quantities of formic acid in the beginning of the reaction, which is a side product of the reaction from glycerol to glycolic acid. After the first hour of the reaction, the selectivity towards glyceric and glycolic acid steadily decreases as a result of their further oxidation towards higher oxidation products (oxalic and formic acid). Furthermore, also the carbon mass balance decreases, which indicates the formation of CO2, which cannot be detected via HPLC.
The observed high selectivities to glycolic acid and, at increased conversions also to formic acid, are frequently observed for glycerol oxidation under basic conditions with non-noble metal catalyst systems.45,78,79 For example Dumeignil et al. reported that alumina supported Ag catalysts also drive the reaction selectivity towards glycolic acid.30
In order to explore the catalyst durability, three recycling experiments were performed with 5-Cu with a reaction time of 3 h for each cycle. As Fig. S5† shows, the glycerol conversion decreases from 44% in the first run to 36% in the second run and shows a minor decrease to 33% in the third run, which indicates a decent stability of the catalyst. To obtain further insights into possible deactivation mechanisms, leaching experiments were performed by removing the solid catalyst after a reaction time of one hour and subsequently preceding the reaction for further two hours without the solid catalyst. The conversion after catalyst removal only slightly increases by 5% from (19% to 24%). Without catalyst removal, a conversion of 44% is observed after 3 h. Thus, leaching of small Cu amounts likely is the major deactivation mechanism (Fig. S6†). Furthermore, EDX analyses of the spent catalyst after 3 h of glycerol oxidation were performed, too. The Cu content from the EDX analysis was 5.6%, which is in good agreement with the initial value (5.2%). The small deviation is well within the error range of the EDX analysis. From the XRD patterns of the spent catalysts after 3 h hours of glycerol oxidation and that after three consecutive runs (3 h each), neither additional crystal phases nor changes of the existing peaks in terms of their relative intensities or shapes are visible (Fig. S7†). The above-mentioned data indicate that the catalyst does not undergo significant structural changes during the catalytic reaction.
Table 1 summarizes the conversions of glycerol after a reaction time of 3 h and the initial reaction rates in water/co-solvent mixtures of various concentrations. The initial reaction rates were calculated from the conversions during the first 1 h of the reaction in which the glycerol conversion changes linearly (Fig. S8†). Without the addition of a co-solvent, the glycerol conversion is 44%. When 5 vol% of PrOH is added to the reaction mixture, the glycerol conversion is increased to 69% and further increases to 70, 73, and 75% at 20, 35 and 50 vol% of PrOH added, respectively. Furthermore, the initial reaction rates also constantly increase from 4.8 mmol h−1 g−1 in the co-solvent-free reaction to 11.0 mmol h−1 g−1 when the reaction is performed in 50 vol% PrOH. Similar trends are also observed when EtOH is employed as a co-solvent, which leads to initial reaction rates as high as 14.2 mmol h−1 g−1, giving a threefold increase of the initial reaction rate compared to the co-solvent-free reaction. Thus, compared to the co-solvent free reaction, the initial reaction rate is three times higher for the reaction performed in 50-EtOH. When BuOH is used as a co-solvent at 5 and 20 vol% solvent contents, the conversion and initial reaction rates firstly decrease compared to the reaction without co-solvent. On the other hand, the rates increase at higher volume percentages of BuOH.
Co solvent | Co-solvent/vol% | Conversiona/% | r 0 /mmol h−1 g−1 |
---|---|---|---|
a Conversion after 3 h of reaction time. b Initial reaction rate constants extrapolated from the conversion at a reaction time of 1 h. Reaction conditions: 30 mg catalyst, 15 mL of 0.05 M aq. glycerol solution, 4:1 NaOH:glycerol, 90 °C, 10 bar oxygen. | |||
— | 0 | 44 | 4.8 |
PrOH | 5 | 69 | 6.4 |
20 | 70 | 7.2 | |
35 | 73 | 8.2 | |
50 | 75 | 10.0 | |
EtOH | 5 | 42 | 4.2 |
20 | 66 | 6.1 | |
35 | 74 | 8.7 | |
50 | 74 | 14.2 | |
BuOH | 5 | 47 | 3.5 |
20 | 51 | 4.1 | |
35 | 53 | 5.2 | |
50 | 56 | 6.3 | |
MeOH | 5 | 6 | 0.2 |
20 | 0 | 0 | |
50 | 0 | 0 |
In contrast to the other investigated solvents, which lead to significantly increased glycerol conversions, the addition of MeOH leads to the complete disappearance of the catalytic activity at 20 and 50 vol%. This can be either explained by poisoning of the active sites by a strong adsorption of methanol or by the preferential oxidation of MeOH over glycerol. However, neither formic acid nor CO2 was observed in the reaction mixture after the reaction in 50 vol% MeOH.
It should be noted that blank experiments without glycerol were performed in water/co-solvent mixtures to observe the oxidation products of the co-solvents. Minor amounts of formic acid were detected only in the cases of 35-EtOH, 50-EtOH, 20-PrOH, 35-PrOH, and 50-PrOH at reaction times exceeding 6 h and these were subtracted from the results of the catalytic experiments.
To explain the increased glycerol conversions in water/co-solvent mixtures, the initial reaction rates are correlated to the ET(30) solvent polarity parameters obtained from the literature.65 The ET(30) value is derived from the solvatochromism of the dye betaine 30 and is a descriptor for the hydrogen bond and electrostatic interactions of solvents.81 Low ET(30) values correspond to low solvent polarities. As mentioned earlier, the polarity of a solvent strongly influences the degree of solvation of reactants, and, consequently, their interaction with the catalyst's surface. Highly polar solvents will strongly solvate polar molecules like glycerol and therefore hinder its adsorption on the catalyst's surface. Correspondingly, it is expected, that less polar solvents (lower ET(30) values) give rise to facilitated glycerol–catalyst interactions, which will result in increased initial reaction rates.58Fig. 6 shows the initial reaction rate as a function of the ET(30) parameters of various water/co-solvent mixtures with different volume fractions.
For each of the water/co-solvent mixtures, a linear relation between the initial reaction rate and the ET(30) parameter can be observed. However, no perfect correlation can be observed. For example, in the cases of 5-EtOH and 5-BuOH, a minor decrease of r0 can be observed, even though the ET(30) values predict an increase of r0. It is plausible that other effects, such as competitive adsorption of the co-solvent at active sites and unfavorable pore diffusion of reactants due to increased viscosity, especially in the case of BuOH/water mixtures, interfere with the beneficial effect of the reduced solvent polarity and thus deteriorate the correlation between ET(30) and r0. Influences of the oxygen solubility were excluded by the unchanged glycerol conversion at increased oxygen pressures (Fig. S4b†) The observed absence of any catalytic activity in the presence of MeOH as a co-solvent can certainly not be explained by pore diffusion effects. As mentioned above, strong adsorption of MeOH species at the active sites could be the reason for the observed trends. Interestingly, the prohibitive nature of MeOH was also reported for other Cu catalyzed oxidation reactions with molecular oxygen very recently.82 To fully understand the diverse solvent influences on the glycerol oxidation over Cu–Al2O3 catalysts, further and more detailed studies are necessary.
Glycerol is produced in large scale from bio oil transesterification with ethanol or methanol.8–10 Consequently, the crude glycerol stream contains large amounts of either methanol or ethanol. Thus, the beneficial effect of EtOH as a co-solvent is the most relevant and interesting observation and was studied in more detail in the following.
To gain further insights into the effect of ethanol as a co-solvent, the reaction time of the glycerol oxidation in 0, 5, 20, 35, and 50 vol% EtOH (0-EtOH, 5-EtOH, 20-EtOH, 35-EtOH, and 50-EtOH) was varied from 0.5 to 16 h (Fig. 7). In the cases of 0-EtOH and 5-EtOH, the rate of glycerol conversion is approximately constant during the first 1.5 h of the reaction. Subsequently, the conversion rate decreases and the glycerol conversion reaches 70% after 16 h. In contrast, the same conversion is reached after only 2 h in 50-EtOH at a constant rate. As the presented data show, the glycerol conversion does not exceed approximately 75% in each case, which is due to the formation of various carboxylic acids like glyceric, glycolic, tartronic, oxalic, and formic acid upon glycerol oxidation, which leads to a decreasing pH in the reaction mixture, and consequently to a reduced activity of the catalyst. Measurements show that the pH of 50-EtOH dropped from the initial value of 12.3 to 9.3 and 8.9 after a reaction of time of 3 and 16 h, respectively. As mentioned before (Fig. S4c†), low pH values mitigate the catalytic activity.
To get further evidence for the limiting effect of the pH, 3 mmol of sodium hydroxide (which is equal to the initial NaOH amount in the reaction mixture) was added to the reaction mixture in 50-EtOH after 2 h of reaction and the reaction was continued for another hour, which led to an increase of the glycerol conversion to 90% (Fig. S9†), which proves that the decreasing pH limits the glycerol conversion. However, even though the conversion of glycerol is limited to approximately 75%, the carbon mass balance strongly decreases after the equilibrium conversion is achieved, which indicates that the oxidation products are being further oxidized to CO2.
The selectivity profiles of the reaction performed in water (Fig. 5) and that of the reactions performed in various water/ethanol mixtures (Fig. 8) show very similar trends. In the initial phase of the reaction, until a conversion of approximately 36% is reached, the selectivities towards glyceric, glycolic, tartronic, and formic acid increase for each water/ethanol mixture (Fig. 8). At this point, the selectivities at isoconversions of 36% towards all observed reaction products are almost identical in each water/ethanol mixture (Table S2†). From this point, until the final conversion of approximately 75% is reached, the selectivities towards higher oxidized C2 and C1 products (formic and oxalic acid) increase at the expense of glyceric and glycolic acid, the selectivities of which decrease during this phase of the reaction. After the final conversion of 75% is reached, the selectivities of the oxidation products (with the exception of formic acid) remain constant and these products do not undergo further oxidation. Solely the selectivity towards formic acid decreases, which indicates that formic acid undergoes further oxidation to CO2, which leads to a significant drop of the carbon mass balance. CO2 forms carbonate species in the basic reaction medium, which cannot be detected via HPLC. Furthermore, it should be noted that, at comparable conversions (below the equilibrium conversion), the carbon mass balances in each water/EtOH mixture are almost identical to the carbon mass balance in water (Fig. 7, Table S2†), which rules out consecutive reactions with the glycerol oxidation products and EtOH.
The highest selectivities are observed at a conversion of approximately 35% in each water/ethanol mixture. Table S2† summarizes the selectivities in each water/ethanol mixture which are almost identical in each case. In 50-ethanol, a lower selectivity towards glyceric acid is observed. This can be explained by the short reaction time (40 minutes), which leads to a significant effect of the initial heat-up phase of 10 minutes on the product selectivities. Thus, it is reasonable to assume that the co-solvent does not influence the reaction mechanism itself, but rather increases the reaction kinetics. The same trend is also observed for the other water/co-solvent mixtures studied (Fig. S10†).
Post-reaction characterization of the spent catalyst was carried out by XRD analysis after a reaction time of 3 h in all 50 vol% water/co-solvent mixtures. The X-ray patterns show no significant change of the catalyst's crystal structure in each case. Furthermore, the Cu content of the spent catalyst after 3 h of glycerol oxidation in 50 vol% ethanol of 5.2% is identical to the initial Cu concentration, which indicates that the solvent mixture does not influence the catalyst's structure, as it was also observed for the reaction performed in water (Fig. S7†).
Footnote |
† Electronic supplementary information (ESI) available: Nitrogen physisorption isotherms and textural parameters of prepared catalysts; Cu 2p XPS spectrum of 5-Cu; glycerol conversions at varying temperatures, oxygen pressures and NaOH:glycerol molar ratios; glycerol conversion after adding additional NaOH during the reaction; selectivity–time profiles in water/ethanol mixtures; selectivities and carbon mass balances at approximate isoconversions; recyclability of the catalyst.; calculations of conversion, selectivity, carbon mass balance, and the initial reaction rate. See DOI: 10.1039/c7cy01451a |
This journal is © The Royal Society of Chemistry 2017 |