Silver & gold-catalyzed routes to furans and benzofurans

Abstract

Silver and gold have become incredibly versatile and mild catalysts for numerous transformations, especially in heterocycle synthesis. For the most prominent of them, i.e. furans, silver and gold, with their unique reactivity and mildness, allow numerous possible routes to highly substituted and/or functionalized furans from a large variety of starting materials. Silver and gold catalysis provide thus the most flexible way to this important family of compounds. The present review describes these silver and gold-catalyzed routes, with some emphasis on mechanistic aspects, and proposes a comparison of both the silver and the gold-catalyzed syntheses of furans.