Different detection and stacking techniques in capillary electrophoresis for metabolomics

Abstract

In the last decade, capillary electrophoresis (CE) has joined other analytical separation techniques that are widely used in metabolomics. The coupling of CE with mass spectrometry (MS) as a detector has become a gold standard. However, many other detection techniques can be also employed, especially in non-targeted metabolomics. In addition, CE offers various stacking approaches that improve the sensitivity. Here, we highlight the use of non-MS detectors as well as stacking approaches in metabolomics since 2014.