Issue 6, 2015
From the journal:

Journal of Materials Chemistry B

Microfibrous borate bioactive glass dressing sequesters bone-bound bisphosphonate in the presence of simulated body fluid†

Chandrani Pramanik,‡a   Tianda Wang,‡b   Sushanta Ghoshal, ORCID logo a   Lina Niu,c   Bradley A. Newcomb,a   Yaodong Liu,a   Carolyn M. Primus,d   Hailan Feng,*b   David H. Pashley,e   Satish Kumar*a  and  Franklin R. Tay*e  

* Corresponding authors

a School of Materials Science and Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA
E-mail: satish.kumar@gatech.edu

b Department of Prosthodontics, Peking University School and Hospital of Stomatology, Beijing, P.R. China
E-mail: kqfenghl@bjmu.edu.cn
Fax: +86 1062173402
Tel: +86 1082195232

c State Key Laboratory of Military Stomatology, School of Stomatology, Fourth Military Medical University, Xi'an, P.R. China

d LECOM School of Dental Medicine, 7046 Owl's Nest Terrace, Bradenton, FL, USA

e Georgia Regents University, Augusta, Georgia, USA
E-mail: ftay@gru.edu
Fax: +1-706-721-6252
Tel: +1-706-7212031

Abstract

Ion exchange occurs between borate bioactive glass and simulated body fluid. Borate bioactive glass dressings may be used for managing bisphosphonate-related osteonecrosis of the jaw through the formation of a complex incorporating leached calcium and borate ions and sequestered bone-bound bisphosphonates.

Graphical abstract: Microfibrous borate bioactive glass dressing sequesters bone-bound bisphosphonate in the presence of simulated body fluid

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Article information

DOI
https://doi.org/10.1039/C4TB02035A
Article type
Communication
Submitted
11 Dec 2014
Accepted
05 Jan 2015
First published
06 Jan 2015

J. Mater. Chem. B, 2015,3, 959-963

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Microfibrous borate bioactive glass dressing sequesters bone-bound bisphosphonate in the presence of simulated body fluid

C. Pramanik, T. Wang, S. Ghoshal, L. Niu, B. A. Newcomb, Y. Liu, C. M. Primus, H. Feng, D. H. Pashley, S. Kumar and F. R. Tay, J. Mater. Chem. B, 2015, 3, 959 DOI: 10.1039/C4TB02035A

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