Issue 16, 2015
From the journal:

Chemical Communications

An electrochemical peptide cleavage-based biosensor for prostate specific antigen detection via host–guest interaction between ferrocene and β-cyclodextrin†

Shunbi Xie,a   Jin Zhang,*b   Yali Yuan,a   Yaqin Chaia  and  Ruo Yuan*a  

* Corresponding authors

a Key Laboratory of Luminescent and Real-Time Analytical Chemistry, Ministry of Education (Southwest University), College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P. R. China
E-mail: yuanruo@swu.edu.cn

b Chongqing Key Laboratory of Environmental Materials & Remediation Technologies (Chongqing University of Arts and Sciences), Chongqing 400715, P. R. China
E-mail: zhangjin@cqwu.edu.cn
Fax: +86-23-68253172
Tel: +86-23-68252277

Abstract

Here we have developed a “signal-on” peptide cleavage-based assay to directly transduce the peptide cleavage events into electrochemical signals via the host–guest interaction between ferrocene (Fc) and β-cyclodextrin (β-CD) for prostate specific antigen (PSA) detection.

Graphical abstract: An electrochemical peptide cleavage-based biosensor for prostate specific antigen detection via host–guest interaction between ferrocene and β-cyclodextrin

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Article information

DOI
https://doi.org/10.1039/C4CC10363G
Article type
Communication
Submitted
28 Dec 2014
Accepted
13 Jan 2015
First published
16 Jan 2015

Chem. Commun., 2015,51, 3387-3390

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An electrochemical peptide cleavage-based biosensor for prostate specific antigen detection via host–guest interaction between ferrocene and β-cyclodextrin

S. Xie, J. Zhang, Y. Yuan, Y. Chai and R. Yuan, Chem. Commun., 2015, 51, 3387 DOI: 10.1039/C4CC10363G

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