Issue 36, 2013

Polymer physics, scaling and heterogeneity in the spatial organisation of chromosomes in the cell nucleus

Abstract

We review some of the recent progresses made by the application of polymer physics to the understanding of the spatial organization of chromosomes in the cell nucleus. In particular, we focus on some scaling properties of the contact probability of pairs of sites, discovered by recent genome-wide experiments exploiting new technologies such as Hi-C methods.

Graphical abstract: Polymer physics, scaling and heterogeneity in the spatial organisation of chromosomes in the cell nucleus

Article information

Article type
Review Article
Submitted
22 May 2013
Accepted
10 Jul 2013
First published
11 Jul 2013

Soft Matter, 2013,9, 8631-8635

Polymer physics, scaling and heterogeneity in the spatial organisation of chromosomes in the cell nucleus

M. Barbieri, A. Scialdone, A. Gamba, A. Pombo and M. Nicodemi, Soft Matter, 2013, 9, 8631 DOI: 10.1039/C3SM51436F

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