Issue 5, 2013

Microfluidic methods for forming liposomes

Abstract

Liposome structures have a wide range of applications in biology, biochemistry, and biophysics. As a result, several methods for forming liposomes have been developed. This review provides a critical comparison of existing microfluidic technologies for forming liposomes and, when applicable, a comparison with their analogous macroscale counterparts. The properties of the generated liposomes, including size, size distribution, lamellarity, membrane composition, and encapsulation efficiency, form the basis for comparison. We hope that this critique will allow the reader to make an informed decision as to which method should be used for a given biological application.

Graphical abstract: Microfluidic methods for forming liposomes

Additions and corrections

Article information

Article type
Critical Review
Submitted
04 Oct 2012
Accepted
04 Dec 2012
First published
05 Dec 2012

Lab Chip, 2013,13, 752-767

Microfluidic methods for forming liposomes

D. van Swaay and A. deMello, Lab Chip, 2013, 13, 752 DOI: 10.1039/C2LC41121K

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