Issue 20, 2012
From the journal:

Chemical Communications

Electrochemical current rectifier as a highly sensitive and selective cytosensor for cancer cell detection†

Hailong Li,ab   Dan Li,a   Jiyang Liu,ab   Yinan Qin,a   Jiangtao Ren,ab   Shanling Xu,a   Yaqing Liu,*a   Dirk Mayer*c  and  Erkang Wang*a  

* Corresponding authors

a State Key Lab of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun
E-mail: yaqingliu@ciac.jl.cn, ekwang@ciac.jl.cn
Fax: (+86) 431 85689711
Tel: (+86) 431 85262003

b Graduate School of the Chinese Academy of Sciences, Beijing 100039, China

c Institute of Complex Systems Bioelectronics, Peter Gruenberg Institute, Research Center Juelich, Germany
E-mail: dirk.mayer@fz-juelich.de

Abstract

Signal amplification originating from electrochemical current rectifier (ECR) was firstly applied to construct a cytosensor for rapid and non-invasive detection of folate receptor-rich cancer cells with high sensitivity. It exhibits a broad linear range with a detection limit as low as 10 cells mL−1 even in the presence of a large number of normal cells.

Graphical abstract: Electrochemical current rectifier as a highly sensitive and selective cytosensor for cancer cell detection

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Supplementary files

Article information

DOI
https://doi.org/10.1039/C2CC17591F
Article type
Communication
Submitted
05 Dec 2011
Accepted
06 Jan 2012
First published
10 Jan 2012

Chem. Commun., 2012,48, 2594-2596

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Electrochemical current rectifier as a highly sensitive and selective cytosensor for cancer cell detection

H. Li, D. Li, J. Liu, Y. Qin, J. Ren, S. Xu, Y. Liu, D. Mayer and E. Wang, Chem. Commun., 2012, 48, 2594 DOI: 10.1039/C2CC17591F

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