Issue 16, 2011
From the journal:

Chemical Communications

Gene delivery with polycationic fullerene hexakis-adducts†

David Sigwalt,ab   Michel Holler,a   Julien Iehl,a   Jean-François Nierengarten,*a   Marc Nothisen,b   Emmanuelle Morinb  and  Jean-Serge Remy*b  

* Corresponding authors

a Laboratoire de Chimie des Matériaux Moléculaires, Université de Strasbourg et CNRS (UMR 7509), Ecole Européenne de Chimie, Polymères et Matériaux (ECPM), 25 rue Becquerel, 67087 Strasbourg Cedex 2, France
E-mail: nierengarten@chimie.u-strasbg.fr

b Laboratoire de Chimie Génétique, CAMB, Université de Strasbourg et CNRS (UMR 7199), Faculté de Pharmacie, 74 route du Rhin, B.P. 60024, 67401 Illkirch, France
E-mail: remy@bioorga.u-strasbg.fr

Abstract

Polyplexes prepared from DNA and globular compact polycationic derivatives constructed around a fullerene hexakis-adduct core have shown remarkable gene delivery capabilities.

Graphical abstract: Gene delivery with polycationic fullerene hexakis-adducts

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Article information

DOI
https://doi.org/10.1039/C0CC05783E
Article type
Communication
Submitted
24 Dec 2010
Accepted
25 Jan 2011
First published
08 Feb 2011

Chem. Commun., 2011,47, 4640-4642

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Gene delivery with polycationic fullerene hexakis-adducts

D. Sigwalt, M. Holler, J. Iehl, J. Nierengarten, M. Nothisen, E. Morin and J. Remy, Chem. Commun., 2011, 47, 4640 DOI: 10.1039/C0CC05783E

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