Issue 13, 2009
From the journal:

Soft Matter

Colloidal particles composed of amphiphilic molecules binding gadolinium complexes and peptides as tumor-specific contrast agents in MRI: physico–chemical characterization

Mauro Vaccaro,a   Gaetano Mangiapia,a   Aurel Radulescu,b   Karin Schillén,c   Gerardino D'Errico,a   Giancarlo Morellid  and  Luigi Paduano*a  

* Corresponding authors

a Dipartimento di Chimica, Università degli Studi di Napoli “Federico II” and CSGI Consorzio Interuniversitario per lo Sviluppo dei Sistemi a Grande Interfase, Via Cinthia, 80126 Naples, Italy
E-mail: luigi.paduano@unina.it
Fax: +39 081 674090
Tel: +39 081 674250

b Institut für Festkörperforsching Forschungszentrum Jülich and Jülich Centre for Neutron Science, Lichtenbergstraße 1, 85748 Garching bei München, Germany

c Physical Chemistry 1, Center for Chemistry and Chemical Engineering, Lund University, P.O. Box 124, SE–221 00 Lund, Sweden

d Dipartimento di Scienze Biologiche and CIRPeB, Via Mezzocannone 16, 80134 Naples, Italy

Abstract

This article highlights our recent achievements on the development and upgrade of new potential tumor-specific contrast agents for magnetic resonance imaging (MRI) based on gadolinium complexes and peptides, assemblied in amphiphilic supramolecular aggregates. The physico–chemical characterization of these aggregates provides novel and interesting opportunities to investigate surfactant aggregation properties, that may be exploited in several applications such as in medical diagnostics or in drug and gene delivery.

Graphical abstract: Colloidal particles composed of amphiphilic molecules binding gadolinium complexes and peptides as tumor-specific contrast agents in MRI: physico–chemical characterization

About
Cited by
Related
Download options Please wait...

Article information

DOI
https://doi.org/10.1039/B820804B
Article type
Highlight
Submitted
20 Nov 2008
Accepted
19 Mar 2009
First published
22 Apr 2009

Soft Matter, 2009,5, 2504-2512

Permissions

Request permissions

Colloidal particles composed of amphiphilic molecules binding gadolinium complexes and peptides as tumor-specific contrast agents in MRI: physico–chemical characterization

M. Vaccaro, G. Mangiapia, A. Radulescu, K. Schillén, G. D'Errico, G. Morelli and L. Paduano, Soft Matter, 2009, 5, 2504 DOI: 10.1039/B820804B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements