Issue 38, 2009

Palladium-catalysed arylative cyclisation of N-allylacetamides with aryl halides yielding benzyl-substituted oxazolines

Abstract

Treatment of N-allylacetamide with aryl halide in the presence of sodium t-butoxide and a palladium catalyst leads to arylative cyclisation to provide the corresponding benzyl-substituted oxazoline in high yield.

Graphical abstract: Palladium-catalysed arylative cyclisation of N-allylacetamides with aryl halides yielding benzyl-substituted oxazolines

Supplementary files

Article information

Article type
Communication
Submitted
30 Jun 2009
Accepted
21 Aug 2009
First published
03 Sep 2009

Chem. Commun., 2009, 5754-5756

Palladium-catalysed arylative cyclisation of N-allylacetamides with aryl halides yielding benzyl-substituted oxazolines

D. Fujino, S. Hayashi, H. Yorimitsu and K. Oshima, Chem. Commun., 2009, 5754 DOI: 10.1039/B912895F

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