Issue 15, 2002
From the journal:

Chemical Communications

5-Propynyluracil·diaminopurine: an efficient base-pair for non-enzymatic transcription of DNA

John C. Chaput,a   Surajit Sinhaa  and  Christopher Switzer*a  

* Corresponding authors

a Department of Chemistry, University of California, Riverside, CA, USA
E-mail: switzer@citrus.ucr.edu
Fax: +1 909-787-4713
Tel: +1 909-787-7266

Abstract

The Up·D base-pair (5-propynyl uracil·diaminopurine) is found to be more effective at non-enzymatic transcription than the corresponding natural T·A pair; under non-enzymatic reaction conditions where the natural T·A base-pair fails, a DNA template bearing Up efficiently directs the incorporation of D into a product RNA strand.

Graphical abstract: 5-Propynyluracil·diaminopurine: an efficient base-pair for non-enzymatic transcription of DNA

About
Cited by
Related
Download options Please wait...

Article information

DOI
https://doi.org/10.1039/B204535D
Article type
Communication
Submitted
10 May 2002
Accepted
10 Jun 2002
First published
20 Jun 2002

Chem. Commun., 2002, 1568-1569

Permissions

Request permissions

5-Propynyluracil·diaminopurine: an efficient base-pair for non-enzymatic transcription of DNA

J. C. Chaput, S. Sinha and C. Switzer, Chem. Commun., 2002, 1568 DOI: 10.1039/B204535D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements