Issue 4, 1984

Functionalization of pyridine via direct metallation

Abstract

The isolation of mixtures of 2-, 3-, and 4-deuteriopyridine, 2-, 3-, and 4-trimethylsilylpyridine, or 2-, 3-, and 4-methylthiopyridine indicates successful metallation of pyridine with a 1 : 1 mixture of BuLi-ButOK in tetrahydrofuran–hexane at ––100 °C.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1984, 257-258

Functionalization of pyridine via direct metallation

J. Verbeek, A. V. E. George, R. L. P. de Jong and L. Brandsma, J. Chem. Soc., Chem. Commun., 1984, 257 DOI: 10.1039/C39840000257

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