Selective N-acylation of kanamycin A
Abstract
The N-acylation of partially trimethylsilylated kanamycin A in acetone has been found to proceed selectively at the 1-N position rather than the usual 6′-N position.
The N-acylation of partially trimethylsilylated kanamycin A in acetone has been found to proceed selectively at the 1-N position rather than the usual 6′-N position.
M. J. Cron, J. G. Keil, J. Lin, M. V. Ruggeri and D. Walker, J. Chem. Soc., Chem. Commun., 1979, 266 DOI: 10.1039/C39790000266
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