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Biomaterials Science

Biomaterials Science is an international high impact journal exploring the underlying science behind the function, interactions and design of biomaterials
Impact Factor 3.831 12 Issues per Year
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Biomater. Sci., 2015, Advance Article
DOI: 10.1039/C5BM00123D, Review Article
This review presents recent examples of applications and functionalization strategies of poly(trimethylene carbonate), its copolymers, and its derivatives to exploit the unique physicochemical properties of the aliphatic polycarbonate backbone.
Biomater. Sci., 2015, Advance Article
DOI: 10.1039/C5BM00163C, Review Article
For the past century, various biomaterials have been used in the treatment of bone defects and fractures.
Biomater. Sci., 2015, Advance Article
DOI: 10.1039/C5BM00067J, Paper
In this paper, we proposed a naturally derived protein cage based pH-responsive delivery system for intracellular prodrug controlled release.
Jingyan Cao, Ran Wang, Ning Gao, Minghui Li, Xuyu Tian, Weili Yang, Ying Ruan, Chunlan Zhou, Guangtian Wang, Xiaoying Liu, Shukun Tang, Yan Yu, Ying Liu, Guangyu Sun, Haisheng Peng and Qun Wang
Biomater. Sci., 2015, Advance Article
DOI: 10.1039/C5BM00161G, Paper
A7RC enhanced the accumulation of paclitaxel liposomes in a neuropilin-1 high expressing breast cancer mouse model and inhibited tumor growth and angiogenesis.
Biomater. Sci., 2015, Advance Article
DOI: 10.1039/C5BM00171D, Paper
A two-stage charge conversional nanogel with ATP/pH-sensitivity was generated. The first-stage charge conversion at tumor extracellular pH can enhance the tumor cellular uptake and the second-stage charge conversion in the acidic intracellular organelles (endo/lysosome) can result in the endosomal escape.
Mohammad Ariful Islam, Emma K. G. Reesor, Yingjie Xu, Harshal R. Zope, Bruce R. Zetter and Jinjun Shi
Biomater. Sci., 2015, Advance Article
DOI: 10.1039/C5BM00198F, Review Article
Schematic representation of various biomaterial-based systems for mRNA delivery: (a) protamine–mRNA complex; (b) lipid nanoparticle; (c) lipid nanoparticle with inorganic compounds (e.g. apatite); (d) cationic polymeric nanoparticle; (e) lipid–polymer hybrid nanoparticles including (i) mRNA–polymer complex core surrounded by a lipid shell and (ii) polymer core surrounded by a lipid shell with mRNA absorbed onto the surface; and (f) gold nanoparticle.
Biomater. Sci., 2015, Advance Article
DOI: 10.1039/C5BM00166H, Review Article
Branched polymers own special properties derived from their intrinsic characteristics. These properties make them ideal candidates to be used as carriers for an improved generation of polymer-drug conjugates.
Hiroshi Inaba, Kenta Fujita and Takafumi Ueno
Biomater. Sci., 2015, Advance Article
DOI: 10.1039/C5BM00210A, Minireview
In this mini-review, current development of biomaterials as carbon monoxide-releasing molecules (CORMs) for intracellular applications is summarized and discussed.
Viktoriya Y. Rybalko, Chantal B. Pham, Pei-Ling Hsieh, David W. Hammers, Melissa Merscham-Banda, Laura J. Suggs and Roger P. Farrar
Biomater. Sci., 2015, Advance Article
DOI: 10.1039/C5BM00233H, Paper
Therapeutic delivery of regeneration-promoting biological factors directly to the site of injury has demonstrated its efficacy in various injury models.
Sujit Kootala, Dmitri Ossipov, Jeroen J. J. P. van den Beucken, Sander Leeuwenburgh and Jöns Hilborn
Biomater. Sci., 2015, Advance Article
DOI: 10.1039/C5BM90034D, Correction
Malihe Kheirabadi, Liyang Shi, Reza Bagheri, Kourosh Kabiri, Jöns Hilborn and Dmitri A. Ossipov
Biomater. Sci., 2015, Advance Article
DOI: 10.1039/C5BM00150A, Paper
Four derivatives of hyaluronic acid (HA) bearing thiol (HA-SH), hydrazide (HA-hy), 2-dithiopyridyl (HA-SSPy), and aldehyde groups (HA-al) afford interpenetrating hydrogel in situ.
Markus Hellmund, Katharina Achazi, Falko Neumann, Bala N. S. Thota, Nan Ma and Rainer Haag
Biomater. Sci., 2015, Advance Article
DOI: 10.1039/C5BM00187K, Paper
Excessive cationic charge density of polyplexes during cellular uptake is still a major hurdle for gene delivery. A systematic study on cytotoxic effects caused by effective charge density related to size showed moderate loaded hPG amines to be higher potential as low/high ones.
Samar Damiati, Sonja Zayni, Angelika Schrems, Elisabeth Kiene, Uwe B. Sleytr, Joël Chopineau, Bernhard Schuster and Eva-Kathrin Sinner
Biomater. Sci., 2015, Advance Article
DOI: 10.1039/C5BM00097A, Paper
The scheme of the cell-free, ribosomal synthesis of a VDAC protein in the presence of an S-layer supported lipid membrane. The VDAC protein is adapted from S. Hiller et al., Science, 2008, 321, 1206–1210.
Biomater. Sci., 2015, Advance Article
DOI: 10.1039/C5BM00085H, Review Article
Fouling of artificial surfaces by biofluids is a plague Biotechnology deeply suffers from. Herein, we inventory the state-of-the-art surface chemistries developed to minimize this effect from both human and animal biosamples.
Christian Mangani, Annamaria Lilienkampf, Marcia Roy, Paul A. de Sousa and Mark Bradley
Biomater. Sci., 2015, Advance Article
DOI: 10.1039/C5BM00121H, Communication
A chemically defined hydrogel HG21, which allows enzyme-free passaging, is a substitute for gelatin allowing standardised and inexpensive mESC culture.
Rebecca L. DiMarco, Ruby E. Dewi, Gabriela Bernal, Calvin Kuo and Sarah C. Heilshorn
Biomater. Sci., 2015, Advance Article
DOI: 10.1039/C5BM00108K, Paper
A family of recombinant, protein-engineered mimics of the extracellular matrix were used to identify the microenvironmental factors that impact the 3D culture efficiency of primary adult intestinal organoids.
Silvana Maione, Ana M. Gil, Georgina Fabregat, Luis J. del Valle, Jordi Triguero, Adele Laurent, Denis Jacquemin, Francesc Estrany, Ana I. Jiménez, David Zanuy, Carlos Cativiela and Carlos Alemán
Biomater. Sci., 2015, Advance Article
DOI: 10.1039/C5BM00160A, Paper
Conducting-polymer–peptide conjugates with controlled properties have been used as soft bioelectroactive supports for cell attachment.

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