Stem Cell-Based Tissue Repair

doi:10.1039/9781849732246

Stem Cell-Based Tissue Repair

Editor(s):

Raphael Gorodetsky, Richard Schäfer,

Publication Details

This book is print only request to be an ebook

ISBN: 978-1-84973-001-3
eISBN: 978-1-84973-224-6
DOI:10.1039/9781849732246

Description

The need for customized stem cell therapies for specific conditions will be a major issue in the coming decades. This unique book by experts in the field reviews the subject as it st...

The need for customized stem cell therapies for specific conditions will be a major issue in the coming decades. This unique book by experts in the field reviews the subject as it stands today. Its coverage includes: basic and applied stem cell research and history; sources of adult stem cells; a comparison of difficulties in derivation, and the applications of embryonic and adult stem cells. Specific topics dealt with include: -advantages and problems associated with stem cell / matrix interactions -stem cell differentiation -difficulties using stem cells for clinical application -stem cell based tissue engineering - myth or reality -stem cells and immunity -natural biological matrices versus synthetic - biocompatibility and integration -stem cell delivery, labeling, imaging and tracking -bioreactors: 2D and 3D cell culturing for in-vitro studies and for stem cell implantation -ethical and safety issues -Good Manufacturing Practice (GMP).

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Book Content
Author Information

PART I: Stem cells sources for practical regenerative medicine
Clinical applications of stem cells
Embryonic and adult HSC
Adult non-hematopoietic stem cells: characterization, isolation
Screening Approaches for the Characterization of Stem Cells for regenerative medicine
Part II: TISSUE REGENERATION and STEM CELL ENGINEERING
MSC as vector for cancer therapies
Promises limitations in adult cell based tissue regeneration
Re-programming stem cells and induced adult stem cells
Culturing non-hematopoietic stem cells and requirements of GMP in stem cell based therapies
Stem cells as vectors of genes
PART III: ORGAN TRAGETTED TISSUE REPAIR WITH STEM CELLS
Regeneration of bone
Regeneration of cartilage
Stem cells based replacement tissue for muscle and heart repair
Regeneration of the vasculature
Regeneration of the pancreas/islets and liver
Treating neurodegenerative tissue with embryonic stem cells
Regeneration of the genitourinary system
Strategies to adjust immunomodulation by adult stem cells
Engineering of stem cell homing and labelling of stem cells

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Stem Cell-Based Tissue Repair

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