Issue 40, 2010
From the journal:

Chemical Communications

Total synthesis of grassypeptolide†

Hui Liu,a   Yuqing Liu,b   Xiangyou Xing,a   Zhengshuang Xu*ab  and  Tao Ye*ab  

* Corresponding authors

a Laboratory of Chemical Genomics, Peking University Shenzhen Graduate School, University Town of Shenzhen, Xili, Nanshan District, Shenzhen, China
E-mail: yet@szpku.edu.cn, xuzs@szpku.edu.cn

b Department of Applied Biology & Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China
E-mail: bctaoye@inet.polyu.edu.hk
Tel: +852 34008722

Abstract

The first total synthesis of grassypeptolide, an anticancer cyclodepsipeptide isolated from marine cyanobacteria, has been achieved in 17 steps and an overall 11.3% yield.

Graphical abstract: Total synthesis of grassypeptolide

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Article information

DOI
https://doi.org/10.1039/C0CC01200A
Article type
Communication
Submitted
30 Apr 2010
Accepted
06 Jul 2010
First published
03 Aug 2010

Chem. Commun., 2010,46, 7486-7488

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Total synthesis of grassypeptolide

H. Liu, Y. Liu, X. Xing, Z. Xu and T. Ye, Chem. Commun., 2010, 46, 7486 DOI: 10.1039/C0CC01200A

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