The selective activation of one methyl ketone enantioface viaσ-binding to a chiral metal template: synthesis and reactivity of rhenium ketone complexes [(η5-C5H5)Re(NO)(PPh3)(η1-Me(R)CO)]+PF6–

Abstract

The title compounds (R = Me, Et, Ph) are synthesized from ketones in high yield, structurally characterized, and shown to undergo highly stereoselective nucleophilic attack; secondary alcohols can be made with 95 to 99% enantiomeric excess (e.e.)