Nanoengineered hollow mesoporous silica nanoparticles for the delivery of antimicrobial proteins into biofilms

Chun Xu; Yan He; Zhihao Li; Yusilawati Ahmad Nor; Qingsong Ye

doi:10.1039/C7TB03201C

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Nanoengineered hollow mesoporous silica nanoparticles for the delivery of antimicrobial proteins into biofilms†

Chun Xu,

^ab Yan He,^a Zhihao Li,^a Yusilawati Ahmad Nor^bc and Qingsong Ye

*^a

Author affiliations

* Corresponding authors

^a School of Dentistry, The University of Queensland, Brisbane, QLD, Australia
E-mail: a.ye@uq.edu.au

^b Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD, Australia

^c Department of Biochemical-Biotechnology Engineering, International Islamic University Malaysia, Jalan Gombak, Kuala Lumpur 53100, Malaysia

Abstract

The delivery of bactericidal proteins into biofilms is challenging. Hollow mesoporous silica nanoparticles with large cone-shaped pores were synthesized to deliver antimicrobial proteins into biofilms and showed enhanced antimicrobial activities.

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Article information

DOI: https://doi.org/10.1039/C7TB03201C
Article type: Communication
Submitted: 12 Dec 2017
Accepted: 02 Mar 2018
First published: 02 Mar 2018

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J. Mater. Chem. B, 2018,6, 1899-1902

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Nanoengineered hollow mesoporous silica nanoparticles for the delivery of antimicrobial proteins into biofilms

C. Xu, Y. He, Z. Li, Y. Ahmad Nor and Q. Ye, J. Mater. Chem. B, 2018, 6, 1899 DOI: 10.1039/C7TB03201C

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Journal of Materials Chemistry B

Nanoengineered hollow mesoporous silica nanoparticles for the delivery of antimicrobial proteins into biofilms†

Abstract

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Nanoengineered hollow mesoporous silica nanoparticles for the delivery of antimicrobial proteins into biofilms

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