Issue 30, 2017
From the journal:

Journal of Materials Chemistry B

In vivo self-assembly induced retention of gold nanoparticles for enhanced photothermal tumor treatment†

Xuefeng Hu,‡ab   Peipei Yang,‡b   Jianping He,a   Ruijie Liang,a   Dechao Niu,a   Hao Wang ORCID logo *b  and  Yongsheng Li ORCID logo *a  

* Corresponding authors

a Lab of Low-Dimensional Materials Chemistry, Key Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai 200237, China
E-mail: ysli@ecust.edu.cn

b CAS Center for Excellence in Nanoscience, CAS Key Laboratory for Biological Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology (NCNST), No. 11 Beiyitiao, Zhongguancun, Beijing, China
E-mail: wanghao@nanoctr.cn

Abstract

We present a simple route to fabricate peptide modified spherical gold nanoparticles (AuNPs@Pep1/Pep2) with enhanced retention performance in tumor sites for improved photothermal treatment (PTT), which was achieved through its in vivo self-assembly triggered by matrix metalloproteinase-2 (MMP-2).

Graphical abstract: In vivo self-assembly induced retention of gold nanoparticles for enhanced photothermal tumor treatment

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Article information

DOI
https://doi.org/10.1039/C7TB01268C
Article type
Communication
Submitted
10 May 2017
Accepted
29 Jun 2017
First published
29 Jun 2017

J. Mater. Chem. B, 2017,5, 5931-5936

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In vivo self-assembly induced retention of gold nanoparticles for enhanced photothermal tumor treatment

X. Hu, P. Yang, J. He, R. Liang, D. Niu, H. Wang and Y. Li, J. Mater. Chem. B, 2017, 5, 5931 DOI: 10.1039/C7TB01268C

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