Synthesis and photophysical, electrochemical, antibacterial, and DNA binding studies of triazinocalix[2]arenes

Abstract

Oxygen bridged highly functionalized novel calix[2]arene[2]triazine derivatives were synthesized from 2,6-pyridinedimethanol and cyanuric chloride. All the synthesized oxacalixarenes showed an absorbance band between 315–339 nm and two emission bands at 269–272 nm and 289–339 nm. All the oxacalixarenes exhibited quasireversible oxidation reduction signals in cyclic voltammetry. The binding properties of the oxacalixarenes towards calf thymus DNA (CT-DNA) were investigated by viscosity measurements, UV-VIS and circular dichorism studies and the oxacalixarenes possess comparable antibacterial activity against B. cereus, S. aureus and E. coli as supported by docking studies.