Nanodispersed UV blockers in skin-friendly silica vesicles with superior UV-attenuating efficiency†
Abstract
Using a pig ear skin model, it is demonstrated that silica vesicles show higher skin safety compared to dense silica nanoparticles with similar sizes. A hydrophobic UV blocker is efficiently dispersed in silica vesicles in an amorphous state, leading to ultrahigh UV-attenuating efficiency and a sun protection factor of 100 in a sunscreen formulation.