Issue 31, 2014
From the journal:

Journal of Materials Chemistry B

pH-responsive hierarchical transformation of charged lipid assemblies within polyelectrolyte gel layers with applications for controlled drug release and MR imaging contrast†

Yi-Fong Huang,a   Wen-Hsuan Chiang,b   Wen-Chia Huang,b   Hsin-Hung Chen,a   Ming-Yin Shen,bc   Sung-Chyr Lin,a   Chorng-Shyan Chernd  and  Hsin-Cheng Chiu*b  

* Corresponding authors

a Department of Chemical Engineering, National Chung Hsing University, Taichung 402, Taiwan

b Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Hsinchu 300, Taiwan
E-mail: hscchiu@mx.nthu.edu.tw

c Department of Surgery, National Taiwan University Hospital-Hsinchu Branch, Hsinchu 300, Taiwan

d Department of Chemical Engineering, National Taiwan University of Science and Technology, Taipei 106, Taiwan

Abstract

A cationic lipid-embedded poly(acrylic acid) (PAAc) gel layer coated on chitosan/superparamagnetic iron oxide nanoparticle (SPION) nanohybrid surfaces effectively modulates drug release and MR imaging contrast by pH-responsive morphological transformation and hierarchical alignment of the lipid assemblies.

Graphical abstract: pH-responsive hierarchical transformation of charged lipid assemblies within polyelectrolyte gel layers with applications for controlled drug release and MR imaging contrast

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Article information

DOI
https://doi.org/10.1039/C4TB00771A
Article type
Communication
Submitted
13 May 2014
Accepted
11 Jun 2014
First published
12 Jun 2014

J. Mater. Chem. B, 2014,2, 4988-4992

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pH-responsive hierarchical transformation of charged lipid assemblies within polyelectrolyte gel layers with applications for controlled drug release and MR imaging contrast

Y. Huang, W. Chiang, W. Huang, H. Chen, M. Shen, S. Lin, C. Chern and H. Chiu, J. Mater. Chem. B, 2014, 2, 4988 DOI: 10.1039/C4TB00771A

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