Issue 51, 2018

Recent development of boronic acid-based fluorescent sensors

Abstract

As Lewis acids, boronic acids can bind with 1,2- or 1,3-diols in aqueous solution reversibly and covalently to form five or six cyclic esters, thus resulting in significant fluorescence changes. Based on this phenomenon, boronic acid compounds have been well developed as sensors to recognize carbohydrates or other substances. Several reviews in this area have been reported before, however, novel boronic acid-based fluorescent sensors have emerged in large numbers in recent years. This paper reviews new boron-based sensors from the last five years that can detect carbohydrates such as glucose, ribose and sialyl Lewis A/X, and other substances including catecholamines, reactive oxygen species, and ionic compounds. And emerging electrochemically related fluorescent sensors and functionalized boronic acid as new materials including nanoparticles, smart polymer gels, and quantum dots were also involved. By summarizing and discussing these newly developed sensors, we expect new inspiration in the design of boronic acid-based fluorescent sensors.

Graphical abstract: Recent development of boronic acid-based fluorescent sensors

Article information

Article type
Review Article
Submitted
26 May 2018
Accepted
08 Aug 2018
First published
20 Aug 2018
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2018,8, 29400-29427

Recent development of boronic acid-based fluorescent sensors

G. Fang, H. Wang, Z. Bian, J. Sun, A. Liu, H. Fang, B. Liu, Q. Yao and Z. Wu, RSC Adv., 2018, 8, 29400 DOI: 10.1039/C8RA04503H

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