Issue 19, 2017, Issue in Progress
From the journal:

RSC Advances

Fluorescent probe with aggregation-induced emission characteristics for targeted labelling and imaging of cancer cells†

Na Peng,‡ab   Rui Xu,‡a   Michelle Si,c   Amanda Victorious,c   Emily Ha,c   Chun-Yu Chang*ab  and  Xiao-Ding Xu ORCID logo *a  

* Corresponding authors

a College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China
E-mail: changcy@whu.edu.cn, xd-xu@whu.edu.cn

b Guangdong Provinivial Key Laboratory of Sugarcane Improvement and Biorefinery, Guangdong Provincial Bioengineering Institute (Guangzhou Sugarcane Industry Research Institute), Guangzhou 510316, China

c Department of Chemical Engineering, University of Waterloo, Waterloo N2L 3G1, Ontario, Canada

Abstract

We report a new peptidyl boronic acid-based fluorescent probe with an aggregation-induced emission (AIE) characteristic. Through specific recognition between the boronic acid group and the cancer-associated sialic acid (SA), this fluorescent probe shows an ability for targeted labelling and imaging of cancer cells.

Graphical abstract: Fluorescent probe with aggregation-induced emission characteristics for targeted labelling and imaging of cancer cells

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Article information

DOI
https://doi.org/10.1039/C6RA25674K
Article type
Paper
Submitted
22 Oct 2016
Accepted
18 Jan 2017
First published
13 Feb 2017
This article is Open Access
Creative Commons BY license

RSC Adv., 2017,7, 11282-11285

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Fluorescent probe with aggregation-induced emission characteristics for targeted labelling and imaging of cancer cells

N. Peng, R. Xu, M. Si, A. Victorious, E. Ha, C. Chang and X. Xu, RSC Adv., 2017, 7, 11282 DOI: 10.1039/C6RA25674K

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