Issue 113, 2015

Direct, rapid, solvent-free conversion of unactivated esters to amides using lithium hydroxide as a catalyst

Abstract

A simple, solvent-free methodology is reported for the direct conversion of esters to amides using lithium hydroxide as a catalyst. The approach allows for the preparation of a range of amide products as well as being applicable to the ring-opening of a representative lactone.

Graphical abstract: Direct, rapid, solvent-free conversion of unactivated esters to amides using lithium hydroxide as a catalyst

Supplementary files

Article information

Article type
Paper
Submitted
29 Jun 2015
Accepted
20 Oct 2015
First published
20 Oct 2015

RSC Adv., 2015,5, 93248-93251

Direct, rapid, solvent-free conversion of unactivated esters to amides using lithium hydroxide as a catalyst

S. A. Miller and N. E. Leadbeater, RSC Adv., 2015, 5, 93248 DOI: 10.1039/C5RA21394K

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