Evaluation and optimization of biomarkers in a primary dysmenorrhea model using ultra performance liquid chromatography coupled with quadrupole-time-of-flight mass spectrometry combined with a support vector machine

Abstract

A comprehensive plasma metabolic profiling analysis method was established to evaluate the potential biomarkers in a primary dysmenorrhea model combined with the method of a support vector machine which optimized the selected potential biomarkers. This is an original report to provide verification for the extensive application of the model both in a laboratory and clinic.