Issue 70, 2015
From the journal:

RSC Advances

Glioma cell-targeting doxorubicin delivery and redox-responsive release using angiopep-2 decorated carbonaceous nanodots†

Jiantao Chen,a   Xingli Cun,a   Shaobo Ruan,a   Yang Wang,a   Yanling Zhang,a   Qin He*a  and  Huile Gao*a  

* Corresponding authors

a Key Laboratory of Drug Targeting and Drug Delivery Systems, West China School of Pharmacy, Sichuan University, No. 17, Block 3, Southern Renmin Road, Chengdu, China
E-mail: gaohuile@scu.edu.cn, qinhe@scu.edu.cn

Abstract

Angiopep-2 modified and doxorubicin loaded carbonaceous nanodots (AN-PEG-DOX-CDs) were synthesized for glioma cell targeting, delivery and redox-responsive release of doxorubicin. Our results provided the possibility of using CDs to construct smart drug delivery systems.

Graphical abstract: Glioma cell-targeting doxorubicin delivery and redox-responsive release using angiopep-2 decorated carbonaceous nanodots

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Article information

DOI
https://doi.org/10.1039/C5RA08245E
Article type
Communication
Submitted
05 May 2015
Accepted
17 Jun 2015
First published
17 Jun 2015

RSC Adv., 2015,5, 57045-57049

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Glioma cell-targeting doxorubicin delivery and redox-responsive release using angiopep-2 decorated carbonaceous nanodots

J. Chen, X. Cun, S. Ruan, Y. Wang, Y. Zhang, Q. He and H. Gao, RSC Adv., 2015, 5, 57045 DOI: 10.1039/C5RA08245E

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