Polystyrene resin supported palladium(0) (Pd@PR) nanocomposite catalyzed synthesis of β-aryl and β,β-diaryl unsaturated scaffolds following tandem approaches

Abstract

A one pot general tandem procedure is described for β-aryl and β,β-diaryl alkenes synthesis following an alternative to the classical approaches by using aryl aldehyde as one of the starting materials. The developed polystyrene resin supported palladium(0) (Pd@PR) nanocomposite has been applied in an unprecedented sequential condensation–decarboxylation–Heck (CDH) and condensation–Heck (CH) strategies to generate the substituted alkenes (C₆(C₆)CC–C, C₆–CC–C₆, and C₆(C₆)CC–CO–C₆ units) under ligand, and additive free milder basic reaction conditions. The added momentous benefit over the classical methodologies is in terms of its multi-component approach to achieve the desired products without tedious step wise purifications.