Copper catalyzed room temperature lactonization of aromatic C–H bond: a novel and efficient approach for the synthesis of dibenzopyranones

Abstract

We have developed a novel and efficient methodology for the intramolecular aryl C–H oxidative lactonization of 2-arylbenzaldehyde using a low-cost CuCl catalyst and TBHP as the oxidant at room temperature. We applied the methodology to the synthesis of a series of dibenzopyranones.