Issue 33, 2014

Efficient catalytic-free method to produce α-aryl cycloalkanones through highly chemoselective coupling of aryl compounds with oxyallyl cations

Abstract

Catalytic-free coupling of aryl compounds and α-halo cycloketones via in situ generated oxyallyl cation intermediates is reported here. The reactions efficiently afford α-naphthol cycloalkanones with moderate to excellent yields. Electron-rich aromatic compounds are also used to produce the corresponding α-aryl cycloalkanones, and in some cases, analytically pure products are obtained after simple filtration followed by evaporation.

Graphical abstract: Efficient catalytic-free method to produce α-aryl cycloalkanones through highly chemoselective coupling of aryl compounds with oxyallyl cations

Supplementary files

Article information

Article type
Paper
Submitted
06 Feb 2014
Accepted
24 Mar 2014
First published
25 Mar 2014

RSC Adv., 2014,4, 17370-17377

Author version available

Efficient catalytic-free method to produce α-aryl cycloalkanones through highly chemoselective coupling of aryl compounds with oxyallyl cations

J. Luo, H. Zhou, J. Hu, R. Wang and Q. Tang, RSC Adv., 2014, 4, 17370 DOI: 10.1039/C4RA01043D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements